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Role of a Functional Human Gene Polymorphism in Stress Responsivity and Addictions
Author(s) -
Kreek MJ
Publication year - 2008
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.2008.5
Subject(s) - clinical pharmacology , addiction , limiting , human genome , medicine , gene , psychology , bioinformatics , genetics , computational biology , psychiatry , genome , biology , mechanical engineering , engineering
Over the past decade, enormous progress has been made in both the technical approaches and the scientific information available for studying the human genome. Therefore, increasingly, scientists have begun to address not just single‐gene disorders but complex disorders. The limiting factor in most of such studies remains appropriate, well‐focused detailed phenotyping of the complex disorders under study, with careful ascertainment of subjects with the specific disorder, as well as healthy control subjects. Clinical Pharmacology & Therapeutics (2008); 83 , 4, 615–618. doi: 10.1038/clpt.2008.5