Adolescents in Clinical Trials | Zendy

Kapogiannis BG | Zendy; Mattison DR | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Adolescents in Clinical Trials

Author(s) -

Kapogiannis BG,

Mattison DR

Publication year - 2008

Publication title -

clinical pharmacology and therapeutics

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.941

H-Index - 188

eISSN - 1532-6535

pISSN - 0009-9236

DOI - 10.1038/clpt.2008.191

Subject(s) - clinical trial , clinical pharmacology , drug development , broad spectrum , psychosocial , dosing , medicine , drug , ethnic group , pharmacology , psychology , psychiatry , political science , chemistry , combinatorial chemistry , law

Drug development is a lengthy, costly, and complex process, with clinical trials essential for characterizing dosing, safety, and efficacy in treated populations. After regulatory approval, aggressive marketing ensures that most drugs are used by a broad spectrum of ages, genders, races, and ethnic groups. Unfortunately, not all groups are adequately represented in clinical trials; adolescents are commonly overlooked. This commentary explores how adolescents are considered during drug development, with a special focus on the influence of inherent psychosocial, biological, ethical, and regulatory issues in their recruitment and participation in clinical studies leading to drug licensing. Clinical Pharmacology & Therapeutics (2008); 84 , 6, 655–659 doi: 10.1038/clpt.2008.191

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research