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Why are diazepam metabolism and polymorphic S ‐mephenytoin hydroxylation associated with each other in white and Korean populations but not in Chinese populations?
Author(s) -
Bertilsson Leif,
Kalow Werner
Publication year - 1993
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.1993.77
Subject(s) - mephenytoin , clinical pharmacology , hydroxylation , pharmacology , pharmacogenetics , diazepam , medicine , metabolism , biology , cyp2c19 , genetics , cytochrome p450 , biochemistry , enzyme , gene , genotype
Clinical Pharmacology and Therapeutics (1993) 53, 608–610; doi: 10.1038/clpt.1993.77