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Local anesthesia blocks the antiemetic action of P6 acupuncture
Author(s) -
Dundee John W,
Ghaly George
Publication year - 1991
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.1991.106
Subject(s) - medicine , anesthesia , antiemetic , premedication , lidocaine , acupuncture , saline , nalbuphine , acupuncture point , methohexital , vomiting , opioid , propofol , alternative medicine , pathology , receptor
The incidence of postoperative illness was monitored for 6 hours in 74 women premedicated with nalbuphine, 10 mg, and undergoing short gynecologic operations of similar duration under methohexital‐nitrous oxide‐oxygen anesthesia. Each patient received P6 acupuncture for 5 minutes at the time of administration of premedication. In random order the site of the acupuncture had been previously infiltrated with normal saline solution in half of the patients and 1% lidocaine in the remaining patients. Postoperative emetic sequelae occurred significantly more often in those who received lidocaine compared with the group that received saline solution. This demonstrates the ability of a local anesthetic administered at the point of stimulation to block the antiemetic action of P6 acupuncture in a manner similar to that shown by others for analgesia. Clinical Pharmacology and Therapeutics (1991) 50 , 78–80; doi: 10.1038/clpt.1991.106