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Low nicotine cigarettes: Cigarette consumption and breath carbon monoxide after one year
Author(s) -
Kanzler Maureen,
Jaffe Jerome H,
Nee John
Publication year - 1983
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.1983.188
Subject(s) - nicotine , tar (computing) , smoke , medicine , anesthesia , consumption (sociology) , cigarette smoke , toxicology , pharmacology , environmental health , chemistry , biology , organic chemistry , computer science , social science , sociology , programming language
Subjects who took part in a 12‐wk study of switching behavior were observed during the subsequent year. Data were obtained for 96 smokers every 3 mo. A sample of smokers who, at 12 wk, had switched to a brand delivering less than half the nicotine of their baseline brand were offered continued monetary incentives to participate for an additional 6 mo (maintenance study). In the maintenance study, subjects continued to smoke low‐nicotine cigarettes during the 6‐mo period in which money and contact reinforcement were continued; maintenance control subjects increased their tar and nicotine exposure significantly. In the follow‐up study of those who had not changed by more than 50%, the original control group, nonswitchers, and moderate switchers did not significantly change their nicotine exposure from what it had been at the end of the initial 12‐wk study. Carbon monoxide (CO) in breath showed remarkably little change across the year despite substantial changes in tar and nicotine exposure. To the extent that CO is involved in smoking‐related disorders, switchers derived little if any benefit from switching to low‐nicotine brands. Clinical Pharmacology and Therapeutics (1983) 34 , 408–415; doi: 10.1038/clpt.1983.188