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Flurbiprofen in dysmenorrhea
Author(s) -
DeLia Julian E,
Emery Maurice G,
Taylor Richard H,
Scott James R
Publication year - 1982
Publication title -
clinical pharmacology and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.941
H-Index - 188
eISSN - 1532-6535
pISSN - 0009-9236
DOI - 10.1038/clpt.1982.129
Subject(s) - flurbiprofen , aspirin , placebo , medicine , clinical pharmacology , anesthesia , drug , pain relief , pharmacology , alternative medicine , pathology
Reports on the efficacy of flurbiprofen for dysmenorrhea conflict. We gave 59 dysmenorrheic patients flurbiprofen (50 mg), aspirin (650 mg), or placebo. Paired drug comparisons showed that patients preferred flurbiprofen and that it was more effective in relief of pain, in allowing patients to pursue normal daily function, and in reducing the need for additional analgesics. Except in patient preference, aspirin was only marginally superior to placebo. There was an increase in minor side effects in the flurbiprofen group, but our results indicate therapeutic utility for flurbiprofen in dysmenorrhea. Clinical Pharmacology and Therapeutics (1982) 32, 76–80; doi: 10.1038/clpt.1982.129