Open AccessAdding delayed recall to the ADAS-cog improves measurement precision in mild Alzheimer’s disease: Implications for predicting instrumental activities of daily living.
Author(s) -
Deborah A. Lowe,
Steve Balsis,
Jared F. Benge,
Rachelle S. Doody
Publication year - 2015
Publication title -
psychological assessment
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.96
H-Index - 140
eISSN - 1939-134X
pISSN - 1040-3590
DOI - 10.1037/pas0000133
Subject(s) - recall , psychology , cognition , alzheimer's disease , cog , activities of daily living , psychometrics , episodic memory , audiology , developmental psychology , clinical psychology , cognitive psychology , disease , psychiatry , medicine , artificial intelligence , computer science , pathology
As research increasingly focuses on preclinical stages of Alzheimer's disease (AD), instruments must be retooled to identify early cognitive markers of AD. A supplemental delayed recall subtest for the Alzheimer's Disease Assessment Scale-cognitive (ADAS-cog; Mohs, Rosen, & Davis, 1983; Rosen, Mohs, & Davis, 1984) is commonly implemented, but it is not known precisely where along the spectrum of cognitive dysfunction this subtest yields incremental information beyond what is gained from the standard ADAS-cog, or whether it can improve prediction of functional outcomes. An item response theory approach can analyze this in a psychometrically rigorous way. Seven hundred eighty-eight patients with AD or amnestic complaints or impairment completed a battery including the ADAS-cog and 2 activities of daily living measures. The delayed recall subtest slightly improved the ADAS-cog's measurement precision in the mild range of cognitive dysfunction and increased prediction of instrumental activities of daily living for individuals with subjective memory impairment.