Functional reserve: The residual variance in instrumental activities of daily living not explained by brain structure, cognition, and demographics. | Zendy

A. Zarina Kraal | Zendy; Lauren Massimo | Zendy; Evan Fletcher | Zendy; Carmen I. Carrión | Zendy; Luis D. Medina | Zendy; Dan Mungas | Zendy; Brandon E. Gavett | Zendy; Sarah Tomazewski Farias | Zendy

Open Access

Functional reserve: The residual variance in instrumental activities of daily living not explained by brain structure, cognition, and demographics.

Author(s) -

A. Zarina Kraal,

Lauren Massimo,

Evan Fletcher,

Carmen I. Carrión,

Luis D. Medina,

Dan Mungas,

Brandon E. Gavett,

Sarah Tomazewski Farias

Publication year - 2021

Publication title -

neuropsychology

Language(s) - English

Resource type - Journals

eISSN - 1931-1559

pISSN - 0894-4105

DOI - 10.1037/neu0000705

Subject(s) - cognitive reserve , psychology , dementia , cognition , activities of daily living , apathy , developmental psychology , clinical psychology , gerontology , disease , psychiatry , medicine , cognitive impairment

Cognitive reserve is a concept that explains individual differences in resilience to brain pathology and susceptibility to poor late-life cognitive outcomes. We evaluate the analogous concept of "Functional Reserve," defined as the difference between observed functional abilities and those predicted by brain structure, cognitive performance, and demographics. This study aims to validate the construct of functional reserve by testing its utility in predicting clinical outcomes and exploring its predictors.

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