Depressive symptoms precede cognitive impairment in de novo Parkinson’s disease patients: Analysis of the PPMI cohort. | Zendy

Jacob D. Jones | Zendy; N Kurniadi | Zendy; Taylor Kuhn | Zendy; Sarah M. Szymkowicz | Zendy; Joseph Bunch | Zendy; Elizabeth Rahmani | Zendy

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Depressive symptoms precede cognitive impairment in de novo Parkinson’s disease patients: Analysis of the PPMI cohort.

Author(s) -

Jacob D. Jones,

N Kurniadi,

Taylor Kuhn,

Sarah M. Szymkowicz,

Joseph Bunch,

Elizabeth Rahmani

Publication year - 2019

Publication title -

neuropsychology

Language(s) - English

Resource type - Journals

eISSN - 1931-1559

pISSN - 0894-4105

DOI - 10.1037/neu0000583

Subject(s) - apathy , mood , depression (economics) , cognition , parkinson's disease , anxiety , psychology , depressive symptoms , disease , cohort , clinical psychology , cognitive impairment , psychiatry , medicine , economics , macroeconomics

Nonmotor symptoms, including depression, anxiety, apathy, and cognitive dysfunction, are common in Parkinson's disease (PD). Although a link between mood symptoms and cognitive impairment in PD has been theorized vis-à-vis striatal dopamine depletion, studies have been inconsistent regarding the relationship between mood symptoms and cognitive function. Inconsistencies may reflect the cross-sectional nature of previous studies. The current study examined the bidirectional longitudinal relationship between mood and cognition.

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