Longitudinal intra-individual variability in neuropsychological performance relates to white matter changes in HIV. | Zendy

Jacob D. Jones | Zendy; Taylor Kuhn | Zendy; Zanjbeel Mahmood | Zendy; Elyse J. Singer | Zendy; Charles H. Hinkin | Zendy; April D. Thames | Zendy

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Longitudinal intra-individual variability in neuropsychological performance relates to white matter changes in HIV.

Author(s) -

Jacob D. Jones,

Taylor Kuhn,

Zanjbeel Mahmood,

Elyse J. Singer,

Charles H. Hinkin,

April D. Thames

Publication year - 2017

Publication title -

neuropsychology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.13

H-Index - 130

eISSN - 1931-1559

pISSN - 0894-4105

DOI - 10.1037/neu0000390

Subject(s) - neuropsychology , neurocognitive , white matter , fractional anisotropy , medicine , neuroimaging , cognition , human immunodeficiency virus (hiv) , psychology , clinical psychology , psychiatry , magnetic resonance imaging , immunology , radiology

Recent studies suggest that intraindividual variability (IIV) of neuropsychological performance may be sensitive to HIV-associated neurologic compromise. IIV may be particularly dependent upon the integrity of frontal-subcortical systems, and therefore may be a meaningful phenotype in HIV. We examined the relationship between change in IIV and white matter integrity among HIV seropositive (HIV+) and HIV seronegative (HIV-) individuals.

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