z-logo
open-access-imgOpen Access
Genetic factors moderate everyday physical activity effects on executive functions in aging: Evidence from the Victoria Longitudinal Study.
Author(s) -
Sherilyn Thibeau,
G. Peggy McFall,
Sandra A. Wiebe,
Kaarin J. Anstey,
Roger A. Dixon
Publication year - 2015
Publication title -
neuropsychology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.13
H-Index - 130
eISSN - 1931-1559
pISSN - 0894-4105
DOI - 10.1037/neu0000217
Subject(s) - longitudinal study , rs6265 , psychology , confirmatory factor analysis , gerontology , physical activity , longitudinal sample , neurotrophic factors , demography , medicine , brain derived neurotrophic factor , developmental psychology , structural equation modeling , physical therapy , sociology , statistics , receptor , mathematics , pathology
Everyday physical activity (EPA) is an important modifiable contributor to age-related variability in executive functioning (EF). However, its role may be moderated by nonmodifiable genetic factors. We tested independent and interactive effects of brain-derived neurotrophic factor (BDNF rs6265) and insulin degrading enzyme (IDE rs6583817) on EF and EPA-EF relationships.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.
Having issues? You can contact us here
Accelerating Research

Address

John Eccles House
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom