Open AccessThe impact of medication nonadherence on the relationship between mortality risk and depression in heart failure.
Author(s) -
Emily C. Gathright,
Mary A. Dolansky,
John Gunstad,
Joseph D. Redle,
Richard Josephson,
Shirley Moore,
Joel W. Hughes
Publication year - 2017
Publication title -
health psychology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.548
H-Index - 164
eISSN - 1930-7810
pISSN - 0278-6133
DOI - 10.1037/hea0000529
Subject(s) - medicine , hazard ratio , depression (economics) , heart failure , confidence interval , proportional hazards model , national death index , economics , macroeconomics
Heart failure affects more than 5 million U.S. adults, and approximately 20% of individuals with heart failure experience depressive symptoms. Depression is detrimental to prognosis in heart failure, conferring approximately a 2-fold increase in mortality risk. Medication nonadherence may help explain this relationship because depressed patients are less likely to adhere to the medication regimen.