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Nitric oxide and tissue destruction
Author(s) -
Kendall HK,
Marshall RI,
Bartold PM
Publication year - 2001
Publication title -
oral diseases
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.953
H-Index - 87
eISSN - 1601-0825
pISSN - 1354-523X
DOI - 10.1034/j.1601-0825.2001.70102.x
Subject(s) - nitric oxide , pathogenesis , intracellular , extracellular , disease , autoimmune disease , medicine , immunology , periodontal disease , chemistry , microbiology and biotechnology , biology , pathology , dentistry
Nitric oxide (NO) is a free radical which has complex roles in both health and disease. It is now recognized that NO is essential for a vast spectrum of intracellular and extracellular events in a wide variety of tissues. NO has also been implicated in the pathogenesis of numerous inflammatory and autoimmune diseases. In this review we consider the roles of NO generally and in particular the implications for periodontal diseases.