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Management of Hepatitis C Infection in Renal Transplant Recipients
Author(s) -
Natov Svetlozar N.,
Pereira Brian J. G.
Publication year - 2002
Publication title -
american journal of transplantation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.89
H-Index - 188
eISSN - 1600-6143
pISSN - 1600-6135
DOI - 10.1034/j.1600-6143.2002.20601.x
Subject(s) - medicine , renal transplant , hepatitis c virus , epidemiology , hepatitis c , population , immunology , disease , liver disease , transplantation , virus , environmental health
Infection with hepatitis C virus (HCV) in renal transplant recipients is associated with an increased risk of death and is the leading cause of post-transplant liver disease. The prevalence of hepatitis C in this population is high. As ascertained by a positive anti-HCV test, between 10 and 41% of the renal transplant recipients are infected with the virus, with a wide variation among different centers and countries (1). Despite impressive advances in our knowledge about the epidemiology, clinical course and management of HCV infection, a number of important questions regarding the care of the HCV-infected renal transplant recipient remain unanswered. In this review, we discuss a comprehensive approach to the management of HCV infection in renal transplant recipients.