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Nuclear Functions for Plasma Membrane‐Associated Proteins?
Author(s) -
Benmerah Alexandre,
Scott Mark,
Poupon Viviane,
Marullo Stefano
Publication year - 2003
Publication title -
traffic
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.677
H-Index - 130
eISSN - 1600-0854
pISSN - 1398-9219
DOI - 10.1034/j.1600-0854.2003.00102.x
Subject(s) - biology , endocytic cycle , microbiology and biotechnology , nucleus , function (biology) , nuclear pore , cell nucleus , transport protein , compartment (ship) , nuclear protein , membrane , cell , endocytosis , biochemistry , transcription factor , gene , oceanography , geology
There are a growing number of observations that proteins, which were initially thought to perform a specific function in a given subcellular compartment, may also play additional roles in different locations within the cell. Proteins found in adhesion and endocytic structures of the plasma membrane and which also traffic to the nucleus perhaps represent the more spectacular examples of this phenomenon. The mechanisms involved in the transport of these molecules through the nuclear pores and their potential nuclear functions are discussed.