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Mitochondrial Inheritance in Budding Yeast
Author(s) -
Boldogh Istvan R.,
Yang HyeongCheol,
Pon Liza A.
Publication year - 2001
Publication title -
traffic
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.677
H-Index - 130
eISSN - 1600-0854
pISSN - 1398-9219
DOI - 10.1034/j.1600-0854.2001.002006368.x
Subject(s) - biology , organelle , microbiology and biotechnology , mitochondrion , saccharomyces cerevisiae , mitochondrial dna , yeast , budding yeast , cell division , cytoskeleton , genetics , extranuclear inheritance , inheritance (genetic algorithm) , mitochondrial fission , cell , gene
During the past decade significant advances were made toward understanding the mechanism of mitochondrial inheritance in the yeast Saccharomyces cerevisiae . A combination of genetics, cell‐free assays and microscopy has led to the discovery of a great number of components. These fall into three major categories: cytoskeletal elements, mitochondrial membrane components and regulatory proteins. These proteins mediate activities, including movement of mitochondria from mother cells to buds, segregation of mitochondria and mitochondrial DNA, and equal distribution of the organelle between mother cells and buds during yeast cell division.