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Associations of leisure‐time physical activity and obesity with atherogenic lipoprotein‐lipid markers among non‐smoking middle‐aged men
Author(s) -
Carroll S.,
Cooke C. B.,
Butterly R. J.,
Gately P.
Publication year - 2001
Publication title -
scandinavian journal of medicine and science in sports
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.575
H-Index - 115
eISSN - 1600-0838
pISSN - 0905-7188
DOI - 10.1034/j.1600-0838.2001.011001038.x
Subject(s) - body mass index , medicine , obesity , endocrinology , cholesterol , national health and nutrition examination survey , demography , population , environmental health , sociology
The association of both leisure‐time physical activity and obesity with lipoprotein‐lipids and composite atherogenic markers were examined within a cross‐sectional study of middle‐aged men of higher socioeconomic status. Analyses were performed on a subsample ( n =629) of non‐smoking, non‐diabetic men (46.7±7.8 years) who completed a preventive medical assessment between 1992 and 1996. Mean adjusted (age, body mass index (BMI), sum of skinfolds, fasting glucose, and logarithmic alcohol consumption) levels of high‐density lipoprotein‐cholesterol (HDL‐C) were significantly higher, and logarithmic triglycerides significantly lower, with higher physical activity index (PAI) categories (both P <0.0001). Significantly lower adjusted mean ratios of both total cholesterol to HDL‐C (TC:HDL‐C), and logarithmic triglycerides to HDL‐C (TG:HDL‐C) with higher PAI were evident following adjustment for the above covariates ( P =0.005 and P <0.0001). Age‐adjusted non‐HDL‐C (total cholesterol minus HDL‐C) decreased significantly with higher PAI categories, but was not significantly lower following covariate adjustment ( P =0.150). On stepwise multiple regression, logarithmic physical activity score and BMI explained 9.5–14% of the variance in the TC:HDL‐C and TG:HDL‐C ratios in models including age, body mass, sum of skinfolds, fasting glucose and logarithmic alcohol consumption. Age, sum of skinfolds and logarithmic alcohol consumption were significant predictors of non‐HDL‐C ( r 2 =8.0%). These findings emphasise the importance of both physical activity and obesity in predicting lipoprotein‐lipid risk markers.