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Chronic actinic dermatitis developed during phototherapy for psoriasis
Author(s) -
Fujii N.,
Uetsu N.,
Hamakawa M.,
Futamura S.,
Okamoto H.,
Horio T.
Publication year - 2002
Publication title -
photodermatology, photoimmunology and photomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.736
H-Index - 60
eISSN - 1600-0781
pISSN - 0905-4383
DOI - 10.1034/j.1600-0781.2002.180311.x
Subject(s) - psoriasis , dermatology , medicine , photosensitizer , puva therapy , plaque psoriasis , chemistry , organic chemistry
A patient with psoriasis vulgaris had been successfully treated with PUVA and UVB therapy. During maintenance phototherapy, he suddenly became photosensitive and developed eczematous eruption. Minimal response doses to UVB and UVA were extremely low – 1.09 mJ/cm 2 and 0.3 J/cm 2 , respectively. No chemical substances were identified as the responsible photosensitizer. The condition was diagnosed as chronic actinic dermatitis (CAD). PUVA therapy was unsatisfactory because it was not possible to administer an adequate dose of UVA. Oral cyclosporine, topical corticosteroid and sunscreen were used with beneficial therapeutic effects on psoriasis and CAD. As far as we know, the development of CAD during phototherapy has not been previously reported.