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Photoonycholysis
Author(s) -
Baran Robert,
Juhlin Lennart
Publication year - 2002
Publication title -
photodermatology, photoimmunology and photomedicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.736
H-Index - 60
eISSN - 1600-0781
pISSN - 0905-4383
DOI - 10.1034/j.1600-0781.2002.00760.x
Subject(s) - erythropoietic protoporphyria , porphyria cutanea tarda , porphyria , dermatology , photosensitivity , medicine , onycholysis , drug , pharmacology , chemistry , protoporphyrin , photochemistry , porphyrin , physics , quantum mechanics , paronychia
Background/Purpose: Photoonycholysis may be seen as a part of Segal's triad, photosensitivity followed by discoloration of the nails and onycholysis. But the latter may also appear, independently, in the absence of photosensitive reaction elsewhere. Methods: Photoonycholysis may result from drug intake, porphyria cutanea tarda, erythropoietic porphyria, erythropoietic protoporphyria, variegate porphyria and pseudoporphyria. Rarely, spontaneous photoonycholysis may be observed. Results: Four distinct subtypes have been recorded without relationship between the responsible drugs and the different clinical varieties of photoonycholysis. Primary photohemorrhage can occur; it can also be associated with polydactylous photoonycholysis type III. Conclusion: The inability to reproduce photoonycholysis experimentally should be emphasized.