Premium
In vitro kinetic evaluation of titanium alloy biodegradation
Author(s) -
Sedarat Cyril,
Harmand MarieFrançoise,
Naji Abdes,
Nowzari Hessam
Publication year - 2001
Publication title -
journal of periodontal research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.31
H-Index - 83
eISSN - 1600-0765
pISSN - 0022-3484
DOI - 10.1034/j.1600-0765.2001.360501.x
Subject(s) - dissolution , titanium , vanadium , atomic absorption spectroscopy , nuclear chemistry , alloy , kinetics , aluminium , metal , chemistry , incubation , titanium alloy , metallurgy , corrosion , in vitro , materials science , biochemistry , physics , quantum mechanics
The present controlled in vitro experiment evaluated the dissolution kinetics of titanium (Ti), aluminum (Al) and vanadium (V). Titanium alloy (Ti 90 Al 6 V 4 ) dental implants were inserted in 1.8 ml sterile tubes, containing equal volumes of NaCl 0.9%(w/v) and human serum. Metallic elements released by the atomic process of corrosion were measured at pH 7.2 and 37°C by atomic absorption spectrophotometer at 1, 3, 6, 9, 15, 21, 27, 33, 42, 51, 60, 69, 78, 87 and 96 days. Ti dissolution averaged 16±5 ng/cm 2 /day and 1565 ng/cm 2 over the experimental period. Al dissolution was stable at 9±5 ng/cm 2 /day and averaged 945 ng/cm 2 over the 96‐day period. V dissolution was stable at 0.15±0.18 ng/cm 2 /day after the sixth day of incubation and averaged 42 ng/cm 2 over the 96‐day period. Major disparities in atomic dissolution were detected among implants. No local or systemic reaction to titanium has been documented. In contrast, 4% toxic V and 6% Al may suffice to elicit local and systemic reactions or inhibit cellular proliferation and differentiation.