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Influences of systemic diseases on periodontitis in children and adolescents
Author(s) -
Meyle Joerg,
Gonzáles José R.
Publication year - 2001
Publication title -
periodontology 2000
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.725
H-Index - 122
eISSN - 1600-0757
pISSN - 0906-6713
DOI - 10.1034/j.1600-0757.2001.2260105.x
Subject(s) - medicine , periodontitis , systemic antibiotics , systemic therapy , systemic disease , antibiotics , intensive care medicine , immunology , dentistry , immunopathology , genetics , cancer , breast cancer , biology
Systemic diseases affecting the host response as primary immunodeficiencies or secondary defects caused by lack of nutrients or changes in the local tissues are very often accompanied by early-onset prepubertal periodontitis. Local treatment in combination with systemic antibiotics may in milder forms improve the situation, but in many cases the success is questionable and premature loss of teeth occurs. Since the genetic basis of many of the diseases has been identified, future developments permit the correction of at least some of these defects by gene therapy.