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Ability of healthy and inflamed human dental pulp to reduce hydrogen peroxide
Author(s) -
Esposito Paola,
Varvara Giuseppe,
Murmura Giovanna,
Terlizzi Antonio,
Caputi Sergio
Publication year - 2003
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1034/j.1600-0722.2003.00062.x
Subject(s) - pulpitis , pulp (tooth) , hydrogen peroxide , catalase , dentistry , chemistry , pulp capping , odontoblast , medicine , enzyme , biochemistry
This study examined the defensive ability of human dental pulp against H 2 O 2 in healthy and reversible and irreversible pulpitis tissues through determination of catalase activity by spectrophotometric methods. Thirty‐five systemically healthy patients were donors of the pulp tissue, and pulp conditions were assessed using clinical and X‐ray evaluations. Catalase activity was 1.61 ± 0.23 U mg −1 protein in the healthy tissues, 2.99 ± 0.45 U mg −1 protein in the reversible pulpitis tissues, and 2.44 ± 467 mU mg −1 protein in the irreversible pulpitis tissues. All differences between the groups were statistically significant. These results point to a role for catalase during dental pulp inflammation in humans, and therefore demonstrate an inherent biological defense system against reactive oxidants in human dental pulp.