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Penetration of an antibacterial dentine‐bonding system into demineralized human root dentine in vitro
Author(s) -
Imazato Satoshi,
Walls Angus W. G.,
Kuramoto Akiko,
Ebisu Shigeyuki
Publication year - 2002
Publication title -
european journal of oral sciences
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.802
H-Index - 93
eISSN - 1600-0722
pISSN - 0909-8836
DOI - 10.1034/j.1600-0722.2002.11221.x
Subject(s) - penetration (warfare) , streptococcus mutans , chemistry , demineralization , bond strength , lactobacillus casei , dentistry , monomer , materials science , bacteria , composite material , adhesive , food science , enamel paint , organic chemistry , medicine , genetics , layer (electronics) , operations research , fermentation , engineering , biology , polymer
In this study, the penetration of three proprietary dentine‐bonding agents (Prime & Bond 2.1, Single Bond, Liner Bond 2) and experimental dentine‐bonding systems incorporating an antibacterial monomer, 12‐methacryloyloxydodecylpyridinium bromide (MDPB), into artificial root caries lesions was evaluated, and the bactericidal activity of each material against Streptococcus mutans or Lactobacillus casei impregnated into demineralized dentine blocks was assessed. All of the commercial dentine‐bonding agents were capable of penetrating into the artificial carious lesions to more than 150 µ m. The depth penetration of the experimental systems, which were based on Liner Bond 2, was not significantly different from that of their parent product. Liner Bond 2 primer exhibited the greatest bactericidal effects among the three proprietary dentine‐bonding agents tested. Bactericidal activities of experimental primers containing MDPB were greater than those of any other products, and the application of 4% MDPB‐containing primer resulted in complete killing of bacteria in demineralized dentine. The results indicate that the penetration of dentine‐bonding agents into extensively demineralized root dentine is possible in vitro , and the experimental dentine‐bonding systems containing the antibacterial monomer MDPB are capable of killing bacteria within demineralized dentine. This could be of benefit when managing root caries lesions.