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Clear cell odontogenic carcinoma with ghost cells and inductive dentin formation – report of a case in the mandible
Author(s) -
Ariyoshi Yasunori,
Shimahara Masashi,
Miyauchi Mutsumi,
Nikai Hiromasa
Publication year - 2002
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1034/j.1600-0714.2002.310310.x
Subject(s) - mandible (arthropod mouthpart) , hyaline , pathology , anatomy , odontogenic tumor , biology , carcinoma , cell , neoplasm , odontogenic , medicine , botany , genetics , genus
An atypical case of clear cell odontogenic carcinoma occurred in the mandible of a 50‐year‐old Japanese man. Microscopically, the tumor mainly consisted of clear, glycogen‐rich epithelial cell nests, aggressively proliferated in the mandible and invading into the surrounding soft tissues. Within the tumor cell nests, clusters of ghost cells were observed in addition to occasional foci of microcystic degeneration. Hyaline, osteoid or dentinoid‐like deposits were also demonstrated adjacent to the tumor cell nests. Dentinal tubules were clearly revealed in some of these structures. Hence, this tumor was regarded as an epithelial neoplasm with odontogenic ectomesenchyme induction.