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Clear cell odontogenic carcinoma of the mandible
Author(s) -
MosquedaTaylor Adalberto,
MenesesGarcía Abelardo,
RuízGodoy Rivera Luz María,
De Lourdes SuárezRoa María
Publication year - 2002
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1034/j.1600-0714.2002.00133.x
Subject(s) - mandible (arthropod mouthpart) , maxilla , medicine , odontogenic tumor , molar , metastasis , odontogenic , carcinoma , mandibular neoplasms , pathology , dentistry , cancer , biology , botany , genus
This article describes a case of clear cell odontogenic carcinoma (CCOC) in a 55‐year‐old woman who presented such a tumor extending from the midline of the mandible to the right first molar. The tumor was surgically excised and has not recurred or metastasized 6 months after surgery. To date, only 33 well‐documented cases have been reported (including the present case) in the English literature. Twenty‐eight (84.8%) have developed in the mandible and five (15.2%) in the maxilla. Eighteen (54.5%) occurred anterior to the first molar. The vast majority have been diagnosed in patients older than 40 years (30/33), and the mean age at diagnosis is 57.4 years (range: 17–89), with a male/female ratio: 1/2. Recurrences have been described in 17 cases (51.5%) and metastasis in 10 (30.3%). Based on its morphologic, histochemical and immunophenotypic features, CCOC should be distinguished from other primary and metastasic clear cell tumors of the oral and maxillofacial regions.