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Oral findings in three different groups of immunocompromised patients
Author(s) -
Meyer Ulrich,
Kleinheinz Johannes,
Handschel Jörg,
KruseLösler Birgit,
Weingart Dieter,
Joos Ulrich
Publication year - 2000
Publication title -
journal of oral pathology and medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.887
H-Index - 83
eISSN - 1600-0714
pISSN - 0904-2512
DOI - 10.1034/j.1600-0714.2000.290402.x
Subject(s) - medicine , immunosuppression , serology , disease , leukemia , oral health , gastroenterology , dentistry , immunology , antibody
The objective of this study was to determine the frequency of oral, dental and periodontal findings in three different groups of immunocompromised patients and in a healthy control group, to evaluate whether there is a correlation between manifestations of disease and immunologic parameters. The survey included 46 patients with a diagnosis of systemic lupus erythematosus, 48 heart transplant recipients, and 53 adult patients suffering from acute leukemias. Fifty matched healthy subjects were used as a control group. Each patient had to answer questions on medical and dental health and underwent a thorough oral, dental and serological investigation. Oral mucosal lesions were found in nearly half of all immunocompromised patients (49.6%), but in only 26% of control patients. No significant associations were found between different types of oral lesions and the underlying cause of immunosuppression. Leukemia patients showed age‐unrelated higher scores in periodontal indices ( P <0.05). Laboratory parameters failed to be significant in the assessment of oral health.