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Serological evidence of alpha herpesvirus infection in sooty mangabeys[Note 1. Funding: This work was supported by NCRR grants RR05062 ...]
Author(s) -
Henkel R.D.,
McClure H.M.,
Krug P.,
Katz D.,
Hilliard J.K.
Publication year - 2002
Publication title -
journal of medical primatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.31
H-Index - 42
eISSN - 1600-0684
pISSN - 0047-2565
DOI - 10.1034/j.1600-0684.2002.01033.x
Subject(s) - serology , macaque , virology , antibody , biology , virus , nonhuman primate , herpesviridae , alpha (finance) , herpesviridae infections , immunology , viral disease , medicine , paleontology , construct validity , nursing , evolutionary biology , patient satisfaction
Contact between sooty mangabeys (SMs) and a pigtailed macaque prompted the serological screening of SMs for evidence of infection with B virus. Serological tests detected SM antibodies that reacted with B virus polypeptides. Additional testing was performed with sera from SMs with no previous contact with macaques. Results from these tests indicated that 56% (33/59) of the SMs had antibodies that reacted with B virus and SA8. SM antibodies also reacted with herpesvirus papio 2 and to a lesser extent with human alpha herpesviruses (HSV‐1 and HSV‐2). There was an age‐related increase in the presence of these antibodies in SMs that was consistent with the serological pattern of reactivity observed in other nonhuman primate species infected with alpha herpesviruses. These data suggest that SMs may be a host for a herpesvirus that is antigenically similar to those viruses present in other Old World nonhuman primates.