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Severe respiratory syncytial virus pneumonia complicating fludarabine and cyclophosphamide treatment of chronic lymphocytic leukemia
Author(s) -
Field K.,
Slavin M.A.,
Seymour J.F.
Publication year - 2002
Publication title -
european journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0902-4441
DOI - 10.1034/j.1600-0609.2002.02745.x
Subject(s) - fludarabine , medicine , ribavirin , pneumonia , cyclophosphamide , chronic lymphocytic leukemia , bronchiolitis , respiratory system , respiratory disease , immunology , virus , leukemia , chemotherapy , lung , hepatitis c virus
The potential for life‐threatening pneumonia due to respiratory syncytial virus (RSV) infection is recognised among patients with acute leukaemia and recipients of allogeneic or autologous bone marrow transplantation. RSV pneumonia has a high mortality rate in these settings. Less intensively treated patients are not usually considered to be at risk for serious RSV pneumonia. We describe the case of a 62‐yr‐old patient with chronic lymphocytic leukaemia (CLL) treated with fludarabine and cyclophosphamide who developed severe RSV pneumonia and recovered following treatment including intravenous ribavirin.

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