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Acute myeloid leukaemia arising from a patient with untreated essential thrombocythaemia
Author(s) -
BolañosMeade Javier,
LópezArvizu Carmen,
Cobos Everardo
Publication year - 2002
Publication title -
european journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0902-4441
DOI - 10.1034/j.1600-0609.2002.02730.x
Subject(s) - medicine , complication , myeloid leukaemia , myeloid , chronic myeloid leukaemia , natural history , pediatrics , surgery
Acute myeloid leukaemia (AML) is an uncommon complication of patients with essential thrombocythaemia (ET). We report a patient with ET which progressed into AML and who had only received a few days of therapy with hydroxyurea (HU) when diagnosed with ET. This is extremely rare, as in large series no patients who were left untreated for their ET developed this complication. This case supports the theory that AML transformation can be part of the natural history of ET in some cases.