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Autoerythrocyte sensitization(Gardner–Diamond) syndrome
Author(s) -
Uthman Imad W.,
Moukarbel George V.,
Salman Salah M.,
Salem Ziad M.,
Taher Ali T.,
Khalil Ismail M.
Publication year - 2000
Publication title -
european journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.904
H-Index - 84
eISSN - 1600-0609
pISSN - 0902-4441
DOI - 10.1034/j.1600-0609.2000.9c234.x
Subject(s) - sensitization , medicine , differential diagnosis , presentation (obstetrics) , emotional stress , purpura (gastropod) , dermatology , surgery , pathology , immunology , ecology , biology
We describe the clinical presentation and course of a patient with autoerythrocyte sensitization (Gardner–Diamond) syndrome, and review the literature for similar cases. A 37‐yr‐old female presented with recurrent episodes of painful ecchymotic bruising over the anterior aspect of both thighs. These episodes were precipitated by emotional stress. The diagnosis was confirmed by induction of similar lesions by intradermal injection of the patient's own washed red blood cells and hemoglobin. The lesions did not recur for 6 months after the cause of her emotional stress was relieved. Autoerythrocyte sensitization (Gardner–Diamond) syndrome should be considered in the differential diagnosis of purpura, especially in patients with psychiatric problems.