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Allergic contact dermatitis from occupational exposure to ranitidine hydrochloride
Author(s) -
Ryan P. J. J.,
Rycroft R. J. G.,
Aston I. R.
Publication year - 2003
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1034/j.1600-0536.2003.480202.x
Subject(s) - ranitidine , sensitization , medicine , ranitidine hydrochloride , contact dermatitis , dermatology , occupational exposure , allergic contact dermatitis , hydrochloride , allergy , pharmacology , chemistry , immunology , medical emergency , organic chemistry
Contact sensitivity to ranitidine hydrochloride has been demonstrated in 6 of 8 symptomatic exposed pharmaceutical manufacturing employees; a 7th has been found to be sensitized to ranitidine base. Although closed manufacturing processes diminish the risk of such sensitization, operatives with potential exposure should be made aware of the importance of avoiding skin contact.