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Occupational allergic contact dermatitis caused by isocyanates
Author(s) -
Goossens A.,
Detienne T.,
Bruze M.
Publication year - 2002
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1034/j.1600-0536.2002.470509.x
Subject(s) - isocyanate , contact dermatitis , allergic contact dermatitis , contact allergy , allergy , occupational exposure , dermatology , patch testing , medicine , polyurethane , chemistry , organic chemistry , immunology , medical emergency
Between 1978 and 2001, 22 patients were diagnosed with occupation‐related allergic contact dermatitis from isocyanates and/or polyurethanes in our clini c . 13 had a positive reaction to the isocyanates, of whom 10 also reacted to diaminodiphenylmethane (MDA), which is used in the production or processing of isocyanates and polyurethanes; 9 reacted only to MDA. The object of the present study was to identify the trades and industries responsible for the development of contact allergy to these resins. Such patients must be patch tested with the isocyanates contacted at work, and account must be taken of positive reactions to MDA as a marker for isocyanate sensitivity.