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Fragrance contact dermatitis – a worldwide multicenter investigation (Part III)
Author(s) -
Larsen Walter,
Nakayama Hideo,
Fischer Torkil,
Elsner Peter,
Frosch Peter,
Burrows Desmond,
Jordan William,
Shaw Stephanie,
Wilkinson John,
Marks James,
Sugawara M.,
Nethercott Marc,
Nethercott James
Publication year - 2002
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1034/j.1600-0536.2002.460302.x
Subject(s) - citronellol , nerol , methyl salicylate , geraniol , organic chemistry , chemistry , lanolin , benzyl benzoate , ether , essential oil , food science , botany , biology
The purpose of this study was to determine the frequency of responses to selected fragrance materials in patients who were fragrance sensitive. 218 fragrance sensitive subjects were evaluated in eight centres worldwide with a fragrance mixture (FM) and 17 less well‐studied fragrance materials. Reaction to the fragrance mixture (FM) occurred in 76% of the subjects. The (FM) detected all reactions to nerol and hydroxycitronellol and 93% of the reactions to clove bud oil. Ten fragrance materials were not detected by the FM and deserve further study: benzenepropanol, beta, beta, 3‐trimethyl, hexyl‐salicylate, dl ‐citronellol, synthetic ylang ylang oil, benzyl mixture, cyclohexyl‐acetate, eugenyl methyl ether, isoeugenyl methyl ether, 3‐phenyl‐1‐propanol, and 3, 7‐dimethyl‐7‐methoxyoctan‐2‐ol.