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Allergic contact dermatitis from sodium dihydroxycetyl phosphate, a new cosmetic allergen?
Author(s) -
Lomholt Hans,
Rastogi Suresh C.,
Andersen Klaus. E.
Publication year - 2001
Publication title -
contact dermatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.524
H-Index - 96
eISSN - 1600-0536
pISSN - 0105-1873
DOI - 10.1034/j.1600-0536.2001.045003143.x
Subject(s) - allergen , allergic contact dermatitis , contact dermatitis , isopropyl alcohol , phosphate , dermatology , chemistry , sodium , medicine , allergy , organic chemistry , immunology
Sodium dihydroxycetyl phosphate (trade name Dragophos S 2/918501) was identified as a contact allergen in a herbal moisturizing cream causing severe acute contact dermatitis on the hands and face of a 41‐year‐old woman. Sodium dihydroxycetyl phosphate is a complex mixture of phosphate esters of dihydroxycetyl alcohol, and subsequent analysis and testing revealed hexadecane‐1,2‐diol as 1 of the allergenic ingredients. Another possible allergen in the compound appears to be hexadecane‐1,2‐diol, 2‐isopropyl ether.