Premium
The effect of a SCN – /H 2 O 2 toothpaste compared to a commercially available triclosan‐containing toothpaste on oral hygiene and gingival health – a 6‐month home‐use study
Author(s) -
Rosin Michael,
Kramer Axel,
Bradtke Detlef,
Richter Gerrit,
Kocher Thomas
Publication year - 2002
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1034/j.1600-051x.2002.291207.x
Subject(s) - toothpaste , triclosan , gingivitis , dentistry , medicine , oral hygiene , carbamide peroxide , fluoride , chemistry , inorganic chemistry , enamel paint , pathology
Objectives: The aim of the study was to compare the gingival health benefits of a thiocyanate/carbamide peroxide toothpaste to that of a triclosan toothpaste in home use. Materials and methods: The study was a two‐centre, randomised, double‐blind, parallel‐group clinical trial, and consisted of a 2‐week pre‐experimental phase, followed by an experimental period of 6 months. A total of 140 healthy male and female volunteers (70 per group) who had at least 20 natural teeth with no probing depths greater than 5 mm and a mean gingival index (GI) of 1 or more at screening were admitted to the study. The two products were the test toothpaste (RCP) containing 0.5% SCN – (rhodanide), carbamide peroxide (equivalent 0.1% H 2 O 2 ), and 1450 p.p.m. fluoride, and a control toothpaste (Colgate Total ® ) containing 0.3% triclosan, 2.0% polyvinyl methyl ether maleic acid (PVM/MA), and 1450 p.p.m. fluoride (Triclosan). In the pre‐experimental phase, all subjects used a fluoride toothpaste. Plaque (Turesky et al. 1970) and gingivitis (Löe & Silness 1963) were scored prior to beginning the pre‐experimental phase, at baseline, and after 6 weeks and 3 and 6 months. Results: In both the RCP and the Triclosan group, gingival health improved significantly between baseline and the following examinations. Plaque scores decreased significantly between baseline and 6 months in both groups. There were, however, no significant differences between the groups for either gingival index or plaque index. Conclusion: To conclude, this study seems to verify that in normal home use, a toothpaste containing a combination of thiocyanate and carbamide peroxide is as effective in reducing gingival inflammation and supragingival plaque formation as a benchmark control product.