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Substantivity of toothpaste slurries and their effect on reestablishment of the dental biofilm
Author(s) -
Arweiler Nicole B.,
Auschill Thorsten M.,
Reich Elmar,
Netuschil Lutz
Publication year - 2002
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1034/j.1600-051x.2002.290705.x
Subject(s) - vitality , dentistry , oral hygiene , dental plaque , toothpaste , gingival inflammation , biofilm , placebo , medicine , toothbrush , gingivitis , biology , bacteria , materials science , pathology , genetics , alternative medicine , brush , composite material
Objectives: Toothpastes are good vehicles for antibacterial substances to exert a prolonged effect. This effect depends on the substantivity and ability to interfere with plaque metabolism and/or vitality. It was the purpose of this clinical, randomized 2 × 4 cell crossover study to evaluate and to compare the antibacterial effects of two toothpastes (Colgate Total®, COL and Parodontax®, PAR) applied as slurries on established plaque over 24 h (Part I) and their effect on 4‐day plaque regrowth (Part II). Chlorhexamed® (0.1%; CHX) and water served as positive and negative controls. Material and methods: After professional toothcleaning eight students were asked to refrain from all mechanical hygiene measures for the next 72 h. After 48 h plaque was sampled and vitality of the plaque flora examined (baseline, VF 0 %). The subjects then rinsed for 1 min with 15 mL of one of the test or control solutions. Every second hour up to 14 h and 24 h after rinsing, plaque sampling and staining was performed to assess plaque vitality (VF 2‐24 , Part I). In Part II, the classical 4‐day plaque regrowth design was used with two rinses (1 min) a day as the only oral hygiene measure. Vitality values were assessed on day 1 and day 4 (VF1, VF2). At day 4, teeth were stained to assess the whole mouth plaque index (PlI) and to evaluate the percentage of plaque area (PA) of the anterior teeth. Results: Compared to placebo, all active rinses reduced plaque vitality significantly over a period of 24 h (Part I). PAR, COL and CHX revealed reductions of 18–31%, 28–50% and 19–50%, respectively. In Part II, similar reductions of all parameters were found for all active rinses (PAR 12–30%, COL 34–51%, CHX 40–64%). Conclusions: Colgate Total has shown a significant action on plaque regrowth and a high substantivity during 24 h, while Parodontax revealed a more moderate but still significant effect.