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Parodontite prépubertaire associée à une maladie granulomateuse chronique: rapport d’un cas
Author(s) -
Buduneli Nurcan,
Baylas Haluk,
Aksu Güzide,
Kütükçüler Necil
Publication year - 2001
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1034/j.1600-051x.2001.028006589.x
Subject(s) - medicine , chronic granulomatous disease , periodontitis , differential diagnosis , periodontology , chronic periodontitis , dermatology , disease , immunodeficiency , pathology , immunology , dentistry , immune system
Background: Generalised prepubertal periodontitis is a rare entity that is usually a consequence of severe systemic diseases. Chronic granulomatous disease is one of the extremely rare inherited immunodeficiency diseases, which predisposes the patient to recurrent severe bacterial and fungal infections. Aim: The purpose of this report is to describe a 5‐year old male patient suffering from prepubertal periodontitis associated with chronic granulomatous disease, who was referred to the Department of Periodontology for treatment of severe gingival inflammation. Methods: A detailed past history was obtained and thorough clinical and laboratory examinations were performed. Results: Medical tests revealed the only immunodeficiency sign as the extremely low burst test result. The patient was diagnosed as having an autosomal recessive (AR) form of chronic granulomatous disease. He was put on prophylactic treatment with trimethoprim‐sulfamethoxazole (TMP‐SMX) and also a periodontal maintenance regimen with regular 1‐month intervals. Conclusion: This case report emphasises the importance of the differential diagnosis of severe immunodeficiency in the background of prepubertal periodontitis.