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Taux de détection de l’Actinobacclus actinomycetemcomitans au niveau des premières molaires permanentes d’écoliers taiwanais par la réaction en chaîne de la polymérase
Author(s) -
Yuan Kuo,
Hsu PingChi,
Tseng ChuenChyi,
Kiang David,
Wang JenRen
Publication year - 2001
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1034/j.1600-051x.2001.028004348.x
Subject(s) - molar , actinobacillus , dentistry , medicine , polymerase chain reaction , aggressive periodontitis , periodontitis , biology , gene , genetics
Background, aims: Actinobacillus actinomycetemcomitans ( Aa ) has been implicated as the putative micro‐organism for localized juvenile periodontitis (LJP). The most distinct clinical features of LJP include severe angular bony defects of the mesial sides of permanent first molars and the onset of disease during puberty. Currently, no large‐scale studies have been performed which address the change in detection rates of Aa on the mesial sides of permanent 1st molars following eruption and up to puberty. Method: In this study, subgingival plaque samples were taken from the mesial pockets of 2 randomly selected permanent 1st molars from 328 primary school children and 50 adult staff, and analyzed by polymerase chain reaction (PCR) to detect Aa . Results: The results showed a 5.5% prevalence rate of Aa which increased after the eruption of 1st molars and peaked near puberty. There were no significant differences in the detection rates of Aa among different groups in terms of gender, plaque index (PlI), and gingival index (GI); however, the higher detection rates of Aa were significantly associated with increased probing depths at p <0.05. Conclusion: PCR analysis of the subgingival plaques demonstrated a prevalence of Aa which peaked near puberty, suggesting that Aa may be important for LJP in Taiwan.