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Regenerative periodontal surgery in interproximal intrabony defects with biodegradable barriers
Author(s) -
Dörfer Christof E.,
Kim TiSun,
Steinbrenner Harald,
Holle Rolf,
Eickholz Peter
Publication year - 2000
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1034/j.1600-051x.2000.027003162.x
Subject(s) - medicine , dentistry , barrier membrane , reduction (mathematics) , surgery , chemistry , membrane , biochemistry , geometry , mathematics
Aim: The comparison of the effects of guided‐tissue regeneration (GTR) using 2 different biodegradable barriers (polylactide acetyltributyl citrate; polydioxanon) in 3‐ and 2‐wall intrabony defects. Method: The polydioxanon barrier is an experimental membrane for GTR therapy that consists of an continuous occlusive barrier that has a layer of slings on the side that is meant to face the mucoperiosteal flap. 15 patients provided 15 pairs of similar contralateral periodontal defects: 12 predominantly 2‐wall and 18 predominantly 3‐wall intrabony defects. Each defect was randomly assigned to treatment with either polylactide acetyltributyl citrate (control [c]) or polydioxanon (test [t]) devices. At baseline and 6 months after surgery, clinical measurements (PlI, GI, PPD, PAL‐V) were performed. Results: Barrier exposure was commonly observed in both groups (control/test): 5/4 after 7 days, 9/11 after 14 days and 11/12 after 28 days postsurgically. 4 weeks after surgery, 77% of all barriers were exposed to some extent. However, both treatments revealed a significant GI reduction ( p <0.05), PPD reduction [−4.63±1.85 mm ( t ), −4.17±1.89 mm (c); p <0.001] and PAL‐V gain [3.97±1.17 mm ( t ), 3.40 mm±1.40 (c); p <0.001] 6 months after surgery. Regarding GI and PPD reduction as well as PAL‐V gain, there were neither statistically significant nor clinically relevant differences between test and control: similar clinical results were found 6 months after surgical treatment using both biodegradable barriers. Conclusions: Based on the results of the present study, the use of both biodegradable barriers in GTR therapy may be recommended.