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The microbiota of periodontal pockets with different depths in therapy‐resistant periodontitis
Author(s) -
Edwardsson Stig,
Bing Ma,
Axtelius Björn,
Lindberg Birgitta,
Söderfeldt Björn,
Attström Rolf
Publication year - 1999
Publication title -
journal of clinical periodontology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.456
H-Index - 151
eISSN - 1600-051X
pISSN - 0303-6979
DOI - 10.1034/j.1600-051x.1999.260303.x
Subject(s) - prevotella intermedia , fusobacterium , actinobacillus , microbiology and biotechnology , bacteroides , fusobacterium nucleatum , periodontitis , peptostreptococcus , porphyromonas gingivalis , prevotella , actinomyces , veillonella , biology , medicine , streptococcus , dentistry , bacteria , genetics
Abstract . This study presents the composition of the cultivable microbiota colonising periodontal pockets of different depths among 2 patient‐groups classified as non‐responsive (NR‐group; 11 participants) or responsive (R‐group; 10 participants) to periodontal treatment. Microbiological samples from three types of pocket (<4 mm deep A‐samples; 4–5 mm B‐samples; >5 mm C‐samples) were analysed by cultural methods for putative periodontitis pathogens, microbial groups constituting ≥5% of the total cultivable flora and opportunistic pathogens. Actinomyces naeslundii , A. israelii , Bacteroides forsythus , Fusobacterium spp, Porphyromonas gingivalis , Prevotella intermedia , Peptostreptococcus micros , anaerobic streptococci and facultative anaerobic streptococci were most prevalent. Actinobacillus actinomycetemcomitans , Staphylococcus aureus , enteric rods and yeasts were less prevalent. The periodontitis pathogens Bacteroides forsythus , Fusobacterium spp, Porphyromonas gingivalis , Prevotella intermedia and Peptostreptococcus micros constituted together (on average) ≤23% of the viable counts in the A‐ and B‐samples of both patient groups and in the C‐samples of the Rgroup. In the C‐samples of the NR‐group their mean counts were 45%. Correlations were found between smoking habits and the five pathogens in the Csamples and in pooled pocket depth samples. The results show that groups of periodontopathogens should be considered a causal factor in therapy‐resistant periodontitis. Further, smoking and deep pockets can enhance a shift in the balance of the subgingival microflora predisposing a site to disease and a susceptible host may be the pre‐requisite to therapy‐resistant periodontitis.