Premium
The biocompatibility (cell culture and histologic study) of hydroxy‐apatite‐coated implants created by ion beam dynamic mixing
Author(s) -
Yoshinari Masao,
Klinge Björn>,
Dérand Tore
Publication year - 1996
Publication title -
clinical oral implants research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.407
H-Index - 161
eISSN - 1600-0501
pISSN - 0905-7161
DOI - 10.1034/j.1600-0501.1996.070202.x
Subject(s) - apatite , biocompatibility , materials science , mixing (physics) , ion beam mixing , focused ion beam , biomedical engineering , ion beam , dentistry , ion , chemistry , mineralogy , metallurgy , medicine , ion beam deposition , physics , organic chemistry , quantum mechanics
Titanium implants were coated with hydroxyapatite by using a method of ion beam dynamic mixing. Coated and noncoated plates of titanium were placed in a growth medium with fibroblast cells. Implant screws, coated and noncoated, were inserted in rabbit bones and the animals were euthanized after 7, 27 and 122 days, respectively. The results from the cell culture test showed no visible difference between the specimens. Histologic examination of implant specimens indicated more new bone activity against coated screws at 27 days, and that was more pronounced at 127 days. Although the amount of new bone formation was not significantly different, certain signs of favourable new bone formation could be seen in contact with coated implants compared to the noncoated controls.