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Effect of membranes and porous hydroxyapatite on healing in bone defects around titanium dental implants. An experimental study in monkeys.
Author(s) -
Gotfredsen K.,
Warrer K.,
Hjörtinghansen E.,
Karring T.
Publication year - 1991
Publication title -
clinical oral implants research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.407
H-Index - 161
eISSN - 1600-0501
pISSN - 0905-7161
DOI - 10.1034/j.1600-0501.1991.020403.x
Subject(s) - titanium , polytetrafluoroethylene , bone grafting , implant , osseointegration , alveolar ridge , dentistry , membrane , materials science , dental implant , grafting , medicine , biomedical engineering , surgery , chemistry , composite material , metallurgy , biochemistry , polymer
The purpose of the present study was to examine the effect of treating bony craters around titanium dental implants with polytetrafluoroethylene membranes PTFE, with and without grafting of hydroxyapatite (HA), and with HA alone. 4 standardized bone defects were prepared in the alveolar ridge of edentulous areas in each of 7 monkeys. A titanium implant was then placed centrally in each defect, and in each monkey, the defects were treated with 1 of the following 4 treament modalities: 1 coverage with PTFE membrane;(2) grafting of HA and covering with a PTFE membrane;(3) HA grafting;(4) no treatment. Following a healing period of 12 weeks, all animals were sacrificed and mesiodistal ground sections of the treated areas were prepared. The histological analysis showed that all bone defects around the implants treated with PTFE membranes and 5 of the defects treated with HA and PTFE membranes were completely filled with new bone. The defects treated with HA alone and the control defects with no treatment only demonstrated new bone formation in the bottom of the defects. The results suggest that bone defects around titanium implants can be 1 treated successfully with PTFE membranes.