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Multiple spindle cell lipomas of the tongue: report of a case
Author(s) -
KAKU NAOMI,
KASHIMA KENJI,
DAA TSUTOMU,
NAKAYAMA IWAO,
KERAKAWAUCHI HIDEOMI,
HASHIMOTO HIROSHI,
YOKOYAMA SHIGEO
Publication year - 2003
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1034/j.1600-0463.2003.1110507.x
Subject(s) - tongue , stroma , lipoma , immunohistochemistry , anatomy , pathology , biology , medicine
Spindle cell lipoma (SCL) is a relatively uncommon benign lipomatous tumor characterized by a mixture of mature adipocytes and bland spindle cells on a fibromyxoid background. These lipomas usually arise as solitary nodules in the subcutaneous tissue of the posterior neck, shoulder and back in adult men. Multiple SCLs account for 0.5% to 3% of all SCLs. In the literature, there have been 15 cases of intraoral SCL, including 6 cases of SCL in the tongue. We report a case of multiple SCLs on the bilateral margins of the tongue of a 75‐year‐old Japanese man. The tumors were removed surgically, and they exhibited the classic histopathological features of SCL, being well‐circumscribed masses composed of a mixture of adipocytes and fibroblast‐like spindle cells within a fibromyxoid stroma. Immunohistochemical analysis revealed that the spindle cells were strongly positive for CD 34 and bcl‐2. To our knowledge, this is the first report of a case of multiple SCLs of the tongue.