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Blood infectivity in transmissible spongiform encephalopathies
Author(s) -
Dickmeiss Ebbe,
Gerstoft Jan
Publication year - 2002
Publication title -
apmis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.909
H-Index - 88
eISSN - 1600-0463
pISSN - 0903-4641
DOI - 10.1034/j.1600-0463.2002.100112.x
Subject(s) - infectivity , transmission (telecommunications) , blood transfusion , virology , disease , creutzfeldt jakob syndrome , medicine , human blood , biology , immunology , virus , prion protein , pathology , physiology , electrical engineering , engineering
Blood infectivity in transmissible spongiform encephalopathies (TSE) is reviewed with special emphasis on transmission by blood transfusion in human beings. It is concluded that transmission by transfusion seems biologically plausible as regards variant Creutzfeld‐Jakob Disease (vCJD), albeit present knowledge suggests that it is extremely uncommon. Precautionary measures against the putative risk of vCJD transmission by blood transfusion are discussed.