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Increased incidence of affective disorders, anxiety disorders, and non‐natural mortality in women after breast cancer diagnosis: a nation‐wide cohort study in Denmark
Author(s) -
Hjerl K.,
Andersen E. W.,
Keiding N.,
Mortensen P. B.,
Jørgensen T.
Publication year - 2002
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1034/j.1600-0447.2002.9028.x
Subject(s) - breast cancer , anxiety , medicine , psychiatry , incidence (geometry) , danish , standardized mortality ratio , cohort , cancer , population , cohort study , anxiety disorder , cancer registry , pediatrics , environmental health , philosophy , physics , linguistics , optics
Objective:  To investigate whether breast cancer patients have increased incidence of psychiatric admission with affective disorders, anxiety disorders, or non‐natural mortality compared with the general female population. Method:  Register‐linkage between nation‐wide registries: The Danish Psychiatric Central Register, The Danish Cancer Registry, and The Danish National Register of Causes of Death. A total of 61 709 women registered with primary invasive breast cancer between 1970 and 1993 were included and 356 023 person‐years were accrued. Results:  The standardized incidence ratio of first‐ever psychiatric admission with affective disorder was 1.49 (95% CI: 1.35–1.63) and with anxiety disorder 1.25 (95% CI: 1.06–1.46). The standardized non‐natural mortality ratio during the first year after breast cancer diagnosis was 1.54 (95% CI: 1.27–1.87). All analyses were adjusted for age, calendar period, and place of residence. Conclusion:  Breast cancer patients have significantly increased incidence of psychiatric admission with affective disorders, anxiety disorders, and non‐natural mortality.

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