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Catatonic stupor induced by neuroleptic in adolescent
Author(s) -
Askenazy F.,
Lestideau K.,
Myquel M.,
Darcourt G.,
Lecrubier Y.
Publication year - 2002
Publication title -
acta psychiatrica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.849
H-Index - 146
eISSN - 1600-0447
pISSN - 0001-690X
DOI - 10.1034/j.1600-0447.106.s413.1_143.x
Subject(s) - stupor , catatonia , haloperidol , neuroleptic malignant syndrome , auditory hallucination , psychology , schizophrenia (object oriented programming) , psychiatry , pediatrics , hallucinating , family history , medicine , psychosis , anesthesia , encephalopathy , artificial intelligence , computer science , dopamine
We present a case report of neuroleptic malignant syndrome with catatonic state (CS) and without pyrexia in a 15‐year‐old‐girl. The onset was acute without previous history of psychotic symptoms. The neuroleptic malignant syndrome occurred after monotherapy with Loxapine (150 mg/day) during 15 days, followed by haloperidol (22.5 mg/day). After an improvement of hallucinatory symptoms, she presents a CS 24 days after a first dose of haloperidol. We describe the case history, and the management of this rare syndrome associated with a high mortality rate. Treatment was medical (parental nutrition hydratation) with intravenous clonazepram. Organic (EEG and MRI abnormalities) and psychiatric symptoms largely overlapped from the onset of CS. Clinical state was characterized by prominent auditory hallucinations and visions. Family history was remarkable for alcoholism, violence, sexual trauma and neurological pathology. Clinical interview released the presence of auditory hallucinations in some young relatives. This case report revealed by: (1) interactions between organic and psychiatric syndrome in catatonia, (2) the possible prodomal function of auditory hallucination in child, (3) the necessity of focusing on relatives in schizophrenia.