Open AccessExpression of transforming growth factor‐β superfamily receptors in rat eyes
Author(s) -
Obata Hiroto,
Kaji Yuichi,
Yamada Hideyuki,
Kato Mitsuyasu,
Tsuru Tadahiko,
Yamashita Hidetoshi
Publication year - 1999
Publication title -
acta ophthalmologica scandinavica
Language(s) - English
Resource type - Journals
eISSN - 1600-0420
pISSN - 1395-3907
DOI - 10.1034/j.1600-0420.1999.770207.x
Subject(s) - medicine , university hospital , general hospital , ophthalmology , library science , family medicine , computer science
Transforming growth factor-beta (TGF-beta) superfamily consists of many multifunctional cytokines including TGF-beta, activins, and bone morphogenetic proteins (BMPs). Previous reports show that these factors are expressed in ocular tissue, and exert their effects through type I and type II serine/threonine type receptors. The purpose of this study is to observe the expression of these receptor families in normal rat eyes as the first step in investigating the functions of TGF-beta superfamily members in ocular tissue.