Open AccessIs 24‐h sperm motility a useful IVF measure when male infertility is not apparent?
Author(s) -
Eskandar Mamdoh
Publication year - 2002
Publication title -
acta obstetricia et gynecologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.401
H-Index - 102
eISSN - 1600-0412
pISSN - 0001-6349
DOI - 10.1034/j.1600-0412.2002.810409.x
Subject(s) - human fertilization , sperm motility , andrology , infertility , in vitro fertilisation , sperm , medicine , male infertility , insemination , unexplained infertility , semen , gynecology , biology , pregnancy , anatomy , genetics
Objective. To examine the relationship of 24‐h sperm motility between post insemination and fertilization in vitro , in a population with no apparent semen abnormalities. A retrospective study from July 1998 to June 2000. Material and methods. Four hundred and seventy‐one consecutive in‐vitro fertilization (IVF) cycles for which the primary diagnosis was not male infertility (total motility count > 40 × 10 6 ) were studied. Linear regression was used to examine the general relation between 24‐h sperm motility and IVF. The cohort with 0% 24‐h motility was compared with all other cycles using the t ‐test and the χ 2 ‐test. Test quality was assessed using the positive likelihood ratio. Results. Overall fertilization was 58 ± 16%. There were 45/471 cycles (9.5%) with zero fertilization. Linear regression of percent fertilization vs. 24‐h motility showed no relationship ( r = 0.01). The cohort with 0% 24‐h motility had a lower fertilization rate 29 ± 19% ( P = 0.05), and had a higher incidence of no fertilization 7/21 ( P = 0.01). The positive likelihood ratio was 4.6. Conclusions. Zero 24‐h motility indicates occult male infertility, and a positive result indicates a fair to good test. Overall there was no relationship between sperm survival at 24 h post insemination and fertilization in vitro . However, 0% 24‐h sperm motility was associated with reduced fertilization