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Diffusion‐weighted MR findings in isolated angiitis of the central nervous system (IACNS)
Author(s) -
Lee S.Y.,
Chu K.,
Park K.I.,
Jeong S.W.,
Yoon B.W.
Publication year - 2003
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1034/j.1600-0404.2003.00134.x
Subject(s) - medicine , effective diffusion coefficient , diffusion mri , differential diagnosis , central nervous system , radiology , cerebral infarction , infarction , ischemia , magnetic resonance imaging , central nervous system disease , pathology , nuclear medicine , cardiology , myocardial infarction
Objectives – To describe the diffusion‐weighted MR (DWI) findings of isolated angiitis of the central nervous system (IACNS) and narrow the differential diagnosis. Methods – The DWI findings of two IACNS patients. Apparent diffusion coefficient (ADC) values were measured in the abnormal lesions, and DWI and T2‐weighted MR images were visually inspected. Results – IACNS was diagnosed based on clinical history, MR findings and cerebral angiographic findings. DWI showed hyperintense lesions with heterogenous ADC values (287–1359 × 10 −6 mm 2 /s), which indicate the coexistence of cytotoxic and vasogenic oedema. Conclusions – The findings suggest that the various stages of inflammatory process with ischaemia might exist in IACNS and allow a differentiation from the usual arterial ischaemic infarction. DWI with ADC map can be a useful non‐invasive diagnostic test increasing specificity in the diagnosis of IACNS, combined with conventional MRI and cerebral angiography.