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Human herpes virus 6 and multiple sclerosis
Author(s) -
Moore F. G. A.,
Wolfson C.
Publication year - 2002
Publication title -
acta neurologica scandinavica
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.967
H-Index - 95
eISSN - 1600-0404
pISSN - 0001-6314
DOI - 10.1034/j.1600-0404.2002.01251.x
Subject(s) - multiple sclerosis , medline , medicine , immunology , biology , biochemistry
Objectives– To systematically review the published evidence for a relationship between human herpes virus 6 (HHV‐6) and multiple sclerosis (MS).Materials and methods– The medical literature was searched using MEDLINE and the Cochrane database. Retrieved studies are presented according to the experimental technique(s) used. The studies are rated for quality usinga prioridefined criteria.Results– Twenty‐eight studies were retrieved. A total of 12 different experimental techniques were used. Four of these techniques provided evidence for a relationship between HHV‐6 and MS, but none were able to show a causative relationship.Conclusions – The available literature provides some support for a relationship between HHV‐6 and MS. The limitations of the available studies and directions for future research are discussed.